Metodesnitazene is a new opioid analgesic with high opioid potential and was created as a substitute for etonitazene and has similar properties. Metodesnitazene can be compared in terms of effects with fentanyl, methadone and approximately has a similar effect on the body: analgesic effects, euphoria, relaxation. Like fentanyl at high dosages, it can cause vomiting and respiratory depression, which can lead to death.