4-AcO-DMT or O-Acetylpsilocin, 4-high-temperature-DMT, or Psilacetin: psychedelic tryptamine. 4-AcO-DMT – acetylated form of psilocybin fungi alkaloid psilocin and lower homologue 4-AcO-DET, 4-AcO-MIPT and 4-AcO-DIPT. The chemical was developed by David Nichols as an alternative to psilocybin for pharmacological studies, as they are both considered prodrugs of psilocin. Structural similarities with psilocybin and psilocin results in a profile with an identical subjective effect and the three compounds feel no different from each other. This allows 4-AcO-DMT as an ideal substitute for psilocybin fungi.




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