Description
Description
4 – Methoxyphencyclidine (methoxydine, 4 – MeO – PCP) is a dissociative anesthetic drug that has been sold online as a research chemical. The synthesis of 4 – MeO – PCP was first reported in 1965 by the Parke – Davis medicinal chemist Victor Maddox. [1] A 1999 review published by a chemist using the pseudonym John Q. Beagle suggested the potency of 4 – MeO – PCP in man was reduced relative to PCP, two years later Beagle published a detailed description of the synthesis and qualitative effects of 4 – MeO – PCP, which he said possessed 70% the potency of PCP. [1] 4 – MeO – PCP was the first arylcyclohexylamine research chemical to be sold online, it was introduced in late 2008 by a company trading under the name CBAY and was followed by several related compounds such as 3 – MeO – PCP and methoxetamine. [1][2] 4 – MeO – PCP has lower affinity for the NMDA receptor than PCP, but higher affinity than ketamine, it is orally active in a dosage range similar to ketamine, with some users requiring doses in excess of 100 mg for desired effects. [1][3] Users have reported substantial differences in active dose, these discrepancies can be partially explained by the presence of unreacted PCC and other impurities in samples sold on the grey market. [1] 4 – MeO – PCP has Ki values of 404 nM for the NMDA receptor, 713 nM for the norepinephrine transporter, 844 nM for the serotonin transporter, 296 nM for the σ1 receptor and 143 nM for the σ2 receptor. [3]
3-MeO-PCP is a synthetic dissociative drug that belongs to the arylcyclohexylamine class. It is primarily used for research purposes, but it has also been reported as a recreational drug and has been associated with a number of adverse health effects. 3-MeO-PCP is a derivative of PCP and is a dissociative. 3-MeO-PCP means 3-Methoxyphencyclidine. This chemical falls into the aryl cyclohexylamine class. It was first synthesized in the entire year 1979. Experiments with 3-MeO-PCP typically yield results that are similar to those of other dissociatives like PCP or MXE. However, researchers have described the results of 3-MeO-PCP to become more stimulating and less immobilizing compared to the results of those other chemicals. Other findings that are generally associated with 3-MeO-PCP include anxiety suppression, disinhibition, cognitive euphoria, conceptual thinking, imagination enhancement, and time distortion.
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Synonyms
3-MeO PCP
3-MeO Phencyclidine
Technical Information
Formal Name
1-[1-(3-methoxyphenyl)cyclohexyl]-piperidine, monohydrochloride
CAS Number
91164-58-8
Molecular Formula
C18H27NO • HCl
Formula Weight
309.9
Purity
≥98%
Formulation
(Request formulation change)
A neat solid
Solubility
(Learn about Variance in Solubility)
DMF: 16 mg/ml
DMSO: 11 mg/ml
Ethanol: 20 mg/ml
PBS (pH 7.2): 10 mg/ml
SMILES
COC1=CC(C2(N3CCCCC3)CCCCC2)=CC=C1.Cl
InChi Code
InChI=1S/C18H27NO.ClH/c1-20-17-10-8-9-16(15-17)18(11-4-2-5-12-18)19-13-6-3-7-14-19;/h8-10,15H,2-7,11-14H2,1H3;1H
InChi Key
MFBXZMQWSUHTBV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 5 years
