Description
MDMA (3,4-methylenedioxy-N-methylamphetamine)
4-Methylamphetamine (4-MA) (hydrochloride) is an analytical reference standard categorized as an amphetamine. 4-MA acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase extracellular levels of these neurotransmitters. In vitro, the potencies of 4-MA for NE and DA release are similar to those of D-amphetamine with EC50 values of 22.2 and 7.2 nM for NE and 44.1 and 8.0 nM for DA, respectively. 4-MA is more potent than D-amphetamine at releasing serotonin (EC50s = 53.4 and 1,756 nM, respectively). In rats, 4-MA acts as an agonist at 5-HT1A receptors and induces hypothermia. It is found as a contaminant in amphetamine, and ingestion has been associated with severe intoxication and fatalities. This product is intended for research and forensic applications.
Synonyms
2,5-Dimethoxy-4-methylamphetamine
STP
Technical Information
Formal Name
2,5-dimethoxy-α,4-dimethyl-benzeneethanamine
CAS Number
15588-95-1
Molecular Formula
C12H19NO2
Formula Weight
209.3
Purity
≥98%
Formulation
(Request formulation change)
A crystalline solid
Solubility
(Learn about Variance in Solubility)
DMF: 14 mg/ml
DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml
DMSO: 5 mg/ml
Ethanol: 10 mg/ml
λmax
224, 292 nm
SMILES
CC1=CC(OC)=C(CC(N)C)C=C1OC
InChi Code
InChI=1S/C12H19NO2/c1-8-5-12(15-4)10(6-9(2)13)7-11(8)14-3/h5,7,9H,6,13H2,1-4H3
InChi Key
NTJQREUGJKIARY-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 5 years
